RP Cure Tracker

Trials / NCT07602803

The Effect of GLP1 Agonists on Weight Loss in BBS Cohort in the UK

Completed Observational Natural history / observational

Sponsor
The Queen Elizabeth Hospital
Treatment
Not listed
Gene
Not stated
Conditions
Bardet-Biedl Syndrome
Ages
18 Years to no upper limit
Enrollment
300 participants
Started
2023-01-01
Main results expected
2026-04-01
Results posted
Not yet
Record last updated
2026-05-27

What the study is testing

The goal of this observational study is to learn about the long-term effects of GLP1 agonists (weight loss jab, including Mounjaro) in patients with Bardet-Biedl Syndrome (BBS) who take GLP1 agonists to treat high body weight. The main question:

Do GLP1 agonists effectively and safely lower body weight in patients with BBS when taken long-term, compared to patients not on these medications? The investigators look at the change (%) in weight during the observational periods.

Where it runs

United Kingdom (1)

Open on ClinicalTrials.gov for contacts and eligibility