Trials / NCT05712148
Spheroidal Mesenchymal Stem Cells in Retinitis Pigmentosa
Completed Phase 1 / Phase 2 Cell therapy
- Sponsor
- Acibadem University
- Treatment
- Stem cell implantation
- Gene
- Not stated
- Conditions
- Retinitis Pigmentosa, Stem Cell Transplant
- Ages
- Any to no upper limit
- Enrollment
- 15 participants
- Started
- 2019-10-11
- Main results expected
- 2022-01-30
- Results posted
- Not yet
- Record last updated
- 2023-02-03
What the study is testing
Purpose: This prospective clinical case series aimed to evaluate the effect of suprachoroidal implantation of mesenchymal stem cells (MSCs) in the form of spheroids as a stem cell therapy for retinitis pigmentosa (RP) patients with relatively good visual acuity.
Methods: Fifteen eyes of 15 patients with RP who received suprachoroidal implantation of MSCs in the form of spheroids were included. Best corrected visual acuity (BCVA), 10-2 and 30-2 visual field examination and multifocal electroretinography (mfERG) recordings were recorded at baseline, postoperative first, third- and sixth-months during follow-up.
Where it runs
Turkey (Türkiye) (1)
- Acıbadem University, Istanbul