Trials / NCT04620876
Bimodal and Coaxial High Resolution Ophtalmic Imaging
Status unknown N/A Other
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- Treatment
- Bimodal high resolution imaging of the retina
- Gene
- Not stated
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema, Retinal Detachment, Retinal Degeneration, Glaucoma, Vascular Inflammation, Hypertension, Stroke, Diabetes
- Ages
- 18 Years to no upper limit
- Enrollment
- 1200 participants
- Started
- 2019-10-01
- Main results expected
- 2023-10-01
- Results posted
- Not yet
- Record last updated
- 2020-11-09
What the study is testing
The knowledge of the pathogenesis of retinal affections, a major cause of blindness, has greatly benefited from recent advances in retinal imaging. However, optical aberrations of the ocular media limit the resolution that can be achieved by current techniques.
The use of an adaptive optics system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many retinal microstructures: photoreceptors, vessels, bundles of nerve fibers.
Recently, the development of the coupling of the two main imaging techniques, the Adaptive Optics Ophthalmoscope with Optical Coherence Tomography, enables unparalleled three-dimensional in vivo cell-scale imaging, while remaining comfortable for the patients.
The purpose of this project is to evaluate the performance of this system for imaging micrometric retinal structures.
Where it runs
France (1)
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris (recruiting now)