Trials / NCT04448860
Validation of Standardized Test Protocols to Assess the Impact of Visual Pathologies in Daily Life Activities
Status unknown N/A Gene therapy, Retinal implant
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- Treatment
- performance of behavioral locomotion tasks phase 1; performance of behavioral locomotion tasks phase 2
- Gene
- Not stated
- Conditions
- Retinitis Pigmentosa
- Ages
- 18 Years to 75 Years
- Enrollment
- 87 participants
- Started
- 2019-10-04
- Main results expected
- 2023-10-04
- Results posted
- Not yet
- Record last updated
- 2020-06-26
What the study is testing
the incidence of the disease of retinal degenerations with loss of photoreceptors (related to old age or genetic) on patients' daily lives, is poorly characterize without standardized means of measurement (usually performed with functional vision or reading tasks).
self-assessment by a quality of life questionnaire correlated with an assessment of emotional state and direct observation of patients during daily life tasks are the two ways used in a scientific framework to collect data on the difficulties encountered by patients in their daily life.
The aim of this project is to determine the behavioral effects of retinitis pigmentosa (RP) by the effects of performance reductions related to adapting to darkness and visual field restriction. Those assessments will be in real conditions but also in virtual reality (VR).
This tool can be used to measure a therapeutic benefit for new treatments (like gene therapy, retinal implants, intra vitreous injections …) for visual loss patients.
Where it runs
France (1)
- Centre hospitalier national d'ophtalmologique de 15-20, Paris (recruiting now)