Trials / NCT04238858
Effects of Subtenon-injected Autologous Platelet-rich Plasma on Visual Functions in Eyes With Retinitis Pigmentosa
Completed N/A Drug / neuroprotection
- Sponsor
- Ankara Universitesi Teknokent
- Treatment
- Platelet rich plasma
- Gene
- Not stated
- Conditions
- Retinitis Pigmentosa
- Ages
- 18 Years to 55 Years
- Enrollment
- 48 participants
- Started
- 2016-09-01
- Main results expected
- 2017-02-28
- Results posted
- Not yet
- Record last updated
- 2020-01-23
What the study is testing
Purpose One of the main reasons for apoptosis and dormant cell phases in degenerative retinal diseases such as retinitis pigmentosa (RP) is growth factor withdrawal in the cellular microenvironment. Growth factors and neurotrophins can significantly slow down retinal degeneration and cell death in animal models. One possible source of autologous growth factors is platelet-richplasma.The purpose of this study was to determine if subtenon injections of autologous platelet-rich plasma (aPRP) can have beneficial effects on visual function in RP patients by reactivating dormant photoreceptors.
Where it runs
Turkey (Türkiye) (1)
- Ankara University Biotechnology Institute, Ankara, Türkiye