Trials / NCT04129021
High Resolution, High-speed Multimodal Ophthalmic Imaging
Recruiting now N/A Device
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- Treatment
- High-resolution retinal imaging through adaptive optics; High-resolution retinal imaging through holographic systems
- Gene
- Not stated
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema, Retinal Detachment, Retinal Degeneration, Glaucoma, Vascular Inflammation, Hypertension, Stroke, Diabetes, Corneal Dystrophy, Keratoconus, Dry Eye, Trauma
- Ages
- 18 Years to no upper limit
- Enrollment
- 1200 participants
- Started
- 2019-07-03
- Main results expected
- 2027-07
- Results posted
- Not yet
- Record last updated
- 2025-11-18
What the study is testing
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye.
The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea.
The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease.
The purpose of this project is to observe structures that are not detectable with routinely used systems.
Where it runs
France (1)
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris (recruiting now)