Trials / NCT02804360
Intravitreal Dexamethasone Implant in Retinitis Pigmentosa-related Macular Edema- a Retrospective Study
Status unknown Phase 2 Drug / neuroprotection
- Sponsor
- Rafic Hariri University Hospital
- Treatment
- dexamethasone injection
- Gene
- Not stated
- Conditions
- Retinitis Pigmentosa, Cystoid Macular Edema
- Ages
- 16 Years to 90 Years
- Enrollment
- 50 participants
- Started
- 2015-01
- Main results expected
- 2016-12
- Results posted
- Not yet
- Record last updated
- 2016-06-20
What the study is testing
Purpose: Cystoid macular edema (CME) in retinitis pigmentosa (RP) has been managed in several ways with little success. The aim of our study was to report the use of intravitreal dexamethasone implant in a large series of patients with RP and CME.
Setting: Retrospective case series. Methods: Cases were diagnosed as RP based on the classic fundus triad of bone-spicule pigment deposits (intraretinal pigmentary migration), retinal vessel attenuation, waxy pallor of the optic disc along with night blindness and attenuated ERG amplitudes (delays in rod or cone b-wave implicit times). Family history of RP and family screening for RP were important in establishing the diagnosis in eyes with some diagnostic challenge. CME was diagnosed by intravitreous fluorescein angiography IVFA and spectral domain optical coherence tomography (SD-OCT). BCVA was monitored using Snellen visual acuity chart and CME was monitored by SD-OCT on follow-up visits.
Where it runs
No sites listed yet.